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Periodic (every 6 months) x-ray examinations of bone age ought to be made throughout remedy of prepubertal patients to find out the speed of bone maturation and the results of androgenic anabolic steroid remedy on the epiphyseal centers.

The validated HPLC method is simple, sensitive, precise, accurate and reproducible. In 1974, the International Olympic Committee decided to add anabolics to the general doping list.

Physicians should be aware of the clinical and underground worlds of AASs and, as with opioids and other potential drugs of abuse, should not allow the abuse of these drugs to limit their appropriate therapeutic use.

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